Thorazine

Thorazine-GlaxoSmithKline-2183-p

Thorazine (chlorpromazine) Coupons, Discounts & Cost

Thorazine (chlorpromazine) is an antipsychotic drug that has a sedative effect. One way to save money on the Thorazine retail cost regardless of income and insurance status is to use Thorazine coupons or discount cards from RXCoupons. Use this Chlorpromazine coupon at this online pharmacy and receive up to 75% off the sale price.

What do I need to know about Thorazine?

Thorazine (chlorpromazine) is an antipsychotic drug that has a sedative effect (when you use high doses). It acts as a sedative by blocking certain adrenoreceptors in the brain.

Chlorpromazine is a substance with antiemetic and moderate antihistaminic effect. This drug reduces blood pressure and causes tachycardia. Chlorpromazine suppresses various types of psychomotor agitation, delirium, hallucinations, fear and anxiety in patients with psychoses and neuroses.

Up to 50% of the active substance is absorbed in the gastrointestinal tract. The maximum concentration can be achieved within 1-2 hours after intramuscular injection and 2-4 hours in case of oral administration.

Thorazine is used for the treatment of endogenous psychoses and certain psychiatric disorders. It is also used to enhance the effect of antihistamines and analgesics. This drug is effective as an antiemetic in patients with Meniere's disease, as well as after chemotherapy. It is also used in the complex treatment of itching dermatoses.

Thorazine indications

In psychiatry: acute and chronic hallucinatory paranoid states, psychomotor agitation in schizophrenia, manic agitation in manic-depressive psychosis, psychotic disorders in epilepsy, alcohol-related psychosis.

In neurology: persistent insomnia, epileptic status.

As antiemetic agent: Meniere's disease, vomiting during pregnancy, treatment with antitumor drugs, radiation therapy.

In dermatology: diseases characterized by itchiness.

In anesthesiology: premedication and potentiation in anesthesia, artificial hypothermia.

What should I discuss with my doctor before taking Thorazine?

Thorazine contraindications: angle-closure glaucoma, urinary retention, multiple sclerosis, Parkinson's disease, myasthenia gravis, chronic heart failure, severe hepatic and renal insufficiency, arterial hypotension, porphyria, children under 3 years of age.

Use with caution in rheumatism (active phase), peptic ulcer, cholelithiasis and urolithiasis, acute pyelitis, hypersensitivity.

The drug is contraindicated during pregnancy and lactation. Minimal maintenance doses should be used if it is not possible to avoid chlorpromazine during pregnancy.

How should I use Thorazine?

Children (depending on age and body weight): - 3-5 years (body weight not more than 23 kg): not more than 40 mg per day; - 5-12 years (body weight not more than 46 kg): 75 mg per day.

Adults: 25-100 mg per day (1-4 doses). If necessary, the dose can be increased by 25-50 mg every 3 days (it should not exceed 1.5 g per day).

The highest daily dose is 1.5 g for oral administration, 150 mg for intramuscular administration and 100 mg for intravenous administration.

What are the possible side effects of Thorazine?

Central and peripheral nervous system: akathisia; rarely - parkinsonian syndrome, thermoregulation disorders, tardive dyskinesia, convulsive syndrome.

Hematopoiesis: agranulocytosis, leukopenia.

Cardiovascular system: tachycardia, arterial hypotension.

Digestive system: dyspeptic disorders, rarely - cholestatic jaundice.

Dermatological reactions: skin pigmentation.

Urinary system: urinary retention.

Reproductive system: disorders of the menstrual cycle, gynecomastia.

Other reactions: blurred vision, phlebitis, allergic reactions.

Overdose symptoms: arterial hypotension, tachycardia, atrioventricular blockade, extrapyramidal symptoms, coma, toxic hepatitis.

Interaction

Drugs that work by depressing the central nervous system (hypnotics, benzodiazepines, non-opioid and opioid analgesics, tricyclic antidepressants, anesthetic agents) may intensify the antihypertensive effect of Thorazine.

MAO inhibitors may cause extrapyramidal disorders (they slow the metabolism of chlorpromazine in the liver).

Antacid agents reduce the absorption of the drug.

Chlorpromazine reduces the effects of levodopa (in case of combination therapy).

Thorazine precautionary measures

Alcohol consumption should be excluded during treatment with chlorpromazine and within 5 days after drug withdrawal.

It is recommended to cancel the drug in case of hyperthermia.

It is not recommended to drive during therapy with chlorpromazine.

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