RYTHMOL (propafenone) Coupons, Discounts & Cost

RYTHMOL (propafenone) Coupons, Discounts & Cost
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Rythmol (propafenone) Coupons, Discounts & Cost

Rythmol (propafenone) is one of the most actively used antiarrhythmic drugs in pediatrics. One way to save money on the Rythmol retail cost regardless of income and insurance status is to use Rythmol coupons or discount cards from RXCoupons. Use this Propafenone coupon at this online pharmacy and receive up to 75% off the sale price.

What should I know about Rythmol?

Rythmol (propafenone) is one of the most actively used antiarrhythmic drugs in pediatrics. It has anesthetic and adrenoblocking effects. This drug is effective in stopping and preventing both ventricular and supraventricular arrhythmias.

The effect starts within 1 hour after ingestion and lasts for 8-12 hours.

Rythmol indications: sustained ventricular tachycardia, life-threatening ventricular arrhythmias, Wolff-Parkinson-White syndrome. This drug can be effective in case of violations of the heart rhythm, persistent ventricular tachycardia, ventricular arrhythmias, etc. This drug should be used only after consultation with a specialist.

Rythmol dose

Individual dose selection is recommended.

The therapeutic dose for patients with a body weight of 70 kg: 450-600 mg per day (150 mg 3 times a day or 300 mg twice a day). In some cases, the dose can be increased to 900 mg (300 mg 3 times a day). Higher doses can be used as an exception.

Patients with a lower body weight should reduce the doses. Elderly patients and patients with severe myocardial damage should increase the doses gradually (at the beginning of treatment).

What are the main Rythmol contraindications?

The drug is contraindicated in patients with cardiogenic shock, refractory heart failure, sinus bradycardia, arterial hypotension, sinoatrial blockade, myasthenia gravis, pronounced electrolyte disturbances, bronchospasm, severe obstructive pulmonary disease, impaired liver or kidney function. In addition, Rythmol is contraindicated in case of pregnancy and breastfeeding.

What should I know about Rythmol side effects?

Cardiovascular system: bradycardia, reduction of myocardial contractility (in predisposed patients), arrhythmogenic effect, orthostatic hypotension (when taken in high doses).

Digestive system: nausea, anorexia, constipation (when taken in high doses); rarely – liver functions violation.

Central nervous system: headache, dizziness (when taken in high doses); rarely – visual impairment.

Hematopoiesis: leukopenia, agranulocytosis, thrombocytopenia.

Reproductive system: oligospermia.

Allergic reactions: rarely – skin rash.

Rythmol interaction

Local anesthetics increase the risk of CNS damage.

Rythmol increases the concentration of cyclosporine and digoxin (the risk of cardiac glycoside toxicity increases).

Rythmol can potentiate the effect of warfarin.

Cimetidine and quinidine may affect the basic metabolic functions of Rythmol. Quinidine inhibits the metabolism of propafenone in individuals, which leads to a significant increase in the concentration of the active substance. In this case, the effectiveness of propafenone does not change. Cimetidine may cause a slight increase in the concentration of propafenone.

The drug increases the level of cyclosporine.

What should I know about Rythmol overdose?

Overdose symptoms: convulsions, hypotension, bradycardia, ventricular arrhythmias, drowsiness or psychomotor agitation, confusion, extrapyramidal disorders.

Treatment: defibrillation, infusion of dopamine and isoproterenol, open chest cardiac massage.

Rythmol specific guidance

It is recommended to monitor the activity of transaminases periodically.

Rythmol is used in reduced doses if liver function is impaired.

The drug is used with caution in patients with violations of liver function, renal dysfunction, as well as in combination with other antiarrhythmics with similar electrophysiological parameters.

It is recommended to stop antiarrhythmic therapy before you start Rythmol therapy.

Propafenone is used in lower doses in elderly patients, as well as in patients with a body weight of less than 70 kg.

Rythmol is used with caution in patients engaged in potentially dangerous activities.

It is possible to use Rythmol during pregnancy only if the intended benefit exceeds the potential risk to the fetus.

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