PROMETRIUM (progesterone) Coupons, Discounts & Cost

PROMETRIUM (progesterone) Coupons, Discounts & Cost
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Prometrium (progesterone) Coupons, Discounts & Cost

Prometrium (progesterone) is a gestagenic drug used to treat infertility. One way to save money on the Prometrium retail cost regardless of income and insurance status is to use Prometrium coupons or discount cards from RXCoupons. Use this Progesterone coupon at this online pharmacy and receive up to 75% off the sale price.

Prometrium indications

Prometrium (progesterone) is a gestagenic drug used to treat infertility. The drug helps reduce excitability and contraction of the uterus and fallopian tubes. It also stimulates the growth of mammary glands.

Prometrium is taken in case of premenstrual syndrome, premenopause, infertility caused by luteal insufficiency, menstrual cycle disorders caused by lack of ovulation, amenorrhea, fibrocystic breast changes. Prometrium is also used as part of hormone replacement therapy for menopause, premature menopause, as well as part of hormone replacement therapy of progesterone deficiency due to the absence of ovaries.

How can I use Prometrium?

Deficit of progesterone: the drug is taken at a dose of 200 mg per day.

Secondary amenorrhea (due to hormonal imbalance): 400 mg once a day (in the evening) for 10 days.

Dysfunctional uterine bleeding: 400 mg per day for 10 days. Bleeding can be stopped within 6 days.

Induction of menstruation: 400 mg per day for 10 days.

Treatment of luteal phase deficiency: 200 or 400 mg for 10 days.

Hormone replacement therapy: take 200 mg per day for 10-12 days.

Preparation for in vitro fertilization: 200-600 mg.

Infertility caused by violations of the yellow body function: 200-300 mg per day.

Prophylaxis of endometrial hyperplasia in postmenopausal patients who use estrogens for hormone replacement therapy: 200 mg 1 time per day before bedtime for 14 days.

Prevention of habitual and threatened miscarriage caused by gestagenic deficiency of the yellow body: 100-200 mg 2 times daily (up to the 12th week of pregnancy).

Oligomenorrhea and pain during menstruation caused by hypogenitalism: 200-300 mg for 10 days. Pain during menstruation: treatment should be started within 6-8 days before menstruation.

Fibrocystic breast disease: 200-300 mg for 10 days.

Prometrium adverse reactions

Prometrium can cause the following side effects: allergies, intermenstrual bleeding, drowsiness, impaired concentration.

Cardiovascular system: high blood pressure.

Metabolism: edema.

Digestive system: jaundice, nausea, vomiting.

Endocrine system: rarely – decreased libido, weight gain, abnormal uterine bleeding.


Griseofulvin, carbamazepine, rifabutin, rifampicin, phenytoin, phenobarbital may reduce the effect of Prometrium.

Carbamazepine, rifabutin, rifampicin, phenytoin, phenobarbital affect the metabolism and reduce the effect of Prometrium.

Progesterone may change the concentrations of glucose.

Cyclosporine may change the concentrations of progesterone.

Progesterone weakens the action of anabolic steroids and drugs that stimulate the smooth muscles of the uterus.

It is not recommended to use Prometrium together with other intravaginal agents.

Prometrium special warnings

Prometrium is contraindicated in porphyria, incomplete abortion, hypersensitivity, thromboembolism, acute phlebitis, bleeding of unknown origin, malignant tumors localized in the mammary glands or genitalia.

Caution is shown when using Prometrium in patients suffering from high blood pressure, chronic renal failure, cardiovascular disease, diabetes, epilepsy, depression, asthma, migraine, hyperlipoproteinemia.

Do not use Prometrium for contraceptive purposes.

Regular gynecological examinations are recommended in order to exclude the risk of endometrial hyperplasia (in case of long-term therapy).

Pregnancy and lactation

It is possible to use progesterone in pregnancy in cases of extreme necessity (in case of deficiency of the hormones of the yellow body). The drug is not used in the late stages of pregnancy.

Progesterone is not used in women planning pregnancy in the near future.

Progesterone penetrates into breast milk. Therefore, it may increase or reduce the quality and quantity of milk (depending on the dose). The drug is contraindicated in the period of breastfeeding.

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