PROCORALAN (ivabradine) Coupons, Discounts & Cost

PROCORALAN (ivabradine) Coupons, Discounts & Cost
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Procoralan (ivabradine) Coupons, Discounts & Cost

Procoralan (ivabradine) is a drug that slows abnormal heart rhythms and improves the heart’s ability to pump blood. One way to save money on the Procoralan retail cost regardless of income and insurance status is to use Procoralan coupons or discount cards from RXCoupons. Use this Ivabradine coupon at this online pharmacy and receive up to 75% off the sale price.

What should I know about Procoralan?

Procoralan (ivabradine) is a drug that slows abnormal heart rhythms and improves the heart’s ability to pump blood. Procoralan therapy is a new safe and effective method for treating severe forms of heart failure.

The drug slows down the rhythm of cardiac contractions without a significant reduction in blood pressure. It can be used alone and together with other drugs (for example, beta-blockers).

Procoralan does not affect intracardiac conduction and contractility of the myocardium (it does not cause negative inotropic effect).

The maximum concentration can be reached within 1 hour. The therapeutic effect occurs within 2-3 weeks after the beginning of therapy.

Procoralan main indications: ivabradine is used for the treatment of stable angina pectoris and chronic heart failure.

What should I know about Procoralan contraindications?

Procoralan is contraindicated in the following cases: cardiogenic shock, sinoatrial block, AV blockade (III degree), hypotension, unstable angina, myocardial infarction, severe hepatic insufficiency, individual intolerance, patients under 18 years of age.

The drug should be used with caution in patients with moderate hepatic insufficiency, renal failure. Caution is prescribed in patients with mild or moderate hypertension. It is not recommended to use this drug for people with lactase deficiency and lactose intolerance.

There is no information about patients who have recently had a stroke. Therefore, Procoralan is not used in these patients.

The effectiveness and safety of the drug has not been studied in adolescents and children under the age of 18 years. Therefore, Procoralan is not used in pediatric practice.

Procoralan is contraindicated during pregnancy and lactation.

What should I know about Procoralan dosage and administration


Take 5 mg 2 times a day. If necessary, the dose may be increased to 7.5 mg 2 times a day (in 3-4 weeks).

The highest daily dose is 15 mg. The highest single dose is 7.5 mg.

A lower dosage is chosen in case of signs of bradycardia (such as hypotension, fatigue, dizziness). Procoralan should be immediately canceled if there was no normalization of the heart rate during treatment.

Procoralan therapy in patients over the age of 75 years starts with a starting dosage of ½ tablets (2.5 mg) 2 times a day (daily dose – 5 mg). You can slightly increase the dosage if the patient’s condition is stable. Use with caution in patients with renal insufficiency.

What should I know about Procoralan side effects?

Central and peripheral nervous system: dizziness, headache, convulsions.

Respiratory system: rarely – shortness of breath.

Hematopoiesis: eosinophilia.

Cardiovascular system: bradycardia (during the first 2-3 months of treatment).

Digestive system: nausea, constipation, diarrhea.

Other organs: blurred vision, allergic reactions.

What should I know about Procoralan overdose?

Overdose symptoms include bradycardia. Treatment is symptomatic.

What should I know about Procoralan interactions?

It is not recommended to take Procoralan with drugs such as ziprasidone, pimozide, sertindole, pentamine, cisapride, erythromycin.

Do not mix Procoralan with grapefruit juice. This may lead to an increase in the concentration of the drug (high risk of bradycardia).

Simultaneous administration with barbiturates, rifampicin, phenytoin, St. John’s wort (Hypericum perforatum) may lead to a decrease in the concentration of ivabradine.

Simultaneous administration with thiazide and loop diuretics leads to hypokalemia (high risk of arrhythmia). Hypokalemia and bradycardia is a predisposing factor for the development of severe arrhythmia.

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