PLAQUENIL (hydroxychloroquine) Coupons, Discounts & Cost

PLAQUENIL (hydroxychloroquine) Coupons, Discounts & Cost
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Plaquenil (hydroxychloroquine) Coupons, Discounts & Cost

Plaquenil (hydroxychloroquine) belongs to the group of anti-malarial and immunosuppressive drugs. One way to save money on the Plaquenil retail cost regardless of income and insurance status is to use Plaquenil coupons or discount cards from RXCoupons. Use this Hydroxychloroquine coupon at this online pharmacy and receive up to 75% off the sale price.

Medical use of the Plaquenil

Plaquenil (hydroxychloroquine) belongs to the group of anti-malarial and immunosuppressive drugs. Plaquenil inhibits malaria pathogens and reduces inflammation. It has a strong immunosuppressive effect (inhibits the activity of the immune system).

Plaquenil is prescribed for rheumatoid arthritis (including juvenile) and lupus erythematosus (systemic and discoid). Plaquenil has been used successfully for the treatment and prevention of acute attacks of malaria provoked by different strains of malaria. Plaquenil has anti-inflammatory and immunosuppressive effect in chronic discoid and systemic lupus erythematosus and acute and chronic rheumatoid arthritis.

Plaquenil dosage and administration

It is recommended to take this drug with 200 ml of milk or with food.

Treatment of rheumatoid arthritis: hydroxychloroquine should be used for several weeks or months, whereas the side effects may occur relatively early. The drug should be discontinued if there is no therapeutic effect after several months of treatment (absence of improvement in the patient’s condition within 6 months of hydroxychloroquine therapy).

Adults (including elderly patients): the drug is prescribed in the lowest effective dose. The dose should not exceed 6.5 mg/kg of body weight per day. The maximum permissible dose is 400 mg per day. The maintenance dose may be increased to 400 mg.

Children: 6.5 mg/kg, but at the same time no more than 200 mg for children who weight less than 31 kg.

Plaquenil can be used in combination with corticosteroids, salicylates, NSAIDs, methotrexate and some other therapeutic agents.

Lupus erythematosus: 400 mg per day for adults (1-2 times a day).

Prevention of acute attacks of malaria: the drug is prescribed in a dose of 400 mg. Take the drug weekly, preferably in the same days of the week.

Acute attack of malaria: 800 mg of Plaquenil, 400 mg after 6-8 hours, and 400 mg for the next two days.

Plaquenil side effects

Plaquenil can cause myopathy, headache, psychosis, convulsions, disturbance of accommodation, tinnitus, retinopathy, keratopathy, blurred vision, atrophy of the optic nerve, AV block, myocardial hypertrophy, loss of appetite, aplastic or hemolytic anemia, abnormal liver function, vomiting, neutropenia, skin rash, abdominal pain. Some reviews include hair loss, skin pigmentation, itching, psoriasis, increased photosensitivity of the skin. Improper use and overdose may lead to dangerous side effects. Excess doses are especially dangerous for children.

Digestive system: nausea, diarrhea, anorexia, abdominal pain; rarely – vomiting, hepatic failure. These reactions usually disappear immediately after dose reduction or discontinuation of treatment.

Central and peripheral nervous system: dizziness, tinnitus, hearing loss, headache, irritability, emotional lability, psychosis, convulsions, muscle weakness, ataxia; in some cases – skeletal muscle weakness leading to progressive weakness and atrophy of proximal muscle groups.

Cardiovascular system: rarely – cardiomyopathy, conduction abnormalities, myocardial hypertrophy of both ventricles, chronic cardiotoxicity.

Hematopoietic system: rarely – inhibition of bone marrow hematopoiesis; in some cases – anemia, aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia.

Metabolism: porphyria.

Dermatological reactions: skin rash, itching, changes in skin pigmentation, alopecia. These reactions usually disappear when you stop treatment.

Allergic reactions: urticaria, angioedema, bronchoconstriction.

Plaquenil contraindications

Plaquenil is contraindicated in case of hypersensitivity to hydroxychloroquine. It is not used in pregnant women. Long-term therapy is contraindicated in children.

Plaquenil should be used with caution in patients with retinopathy, psychosis, psoriasis, porphyria, kidney or liver failure, hepatitis.

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