NORLUTATE (norethindrone) Coupons, Discounts & Cost

NORLUTATE (norethindrone) Coupons, Discounts & Cost
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Norlutate (norethindrone) Coupons, Discounts & Cost

Norlutate (norethindrone) is a synthetic hormonal drug for the treatment of endometrial disorders. One way to save money on the Norlutate retail cost regardless of income and insurance status is to use Norlutate coupons or discount cards from RXCoupons. Use this Norethindrone coupon at this online pharmacy and receive up to 75% off the sale price.

Drug information

Norlutate (norethindrone) is a synthetic hormonal drug for the treatment of endometrial disorders. Norethindrone causes uterine lining transformation. It reduces the excitability and contractility of the muscles of the uterus, inhibits the secretion of pituitary gonadotropins, and prevents the maturation of follicles and ovulation.

Norlutate indications: secondary amenorrhea (lack of normal menstrual cycles for a period of more than 6 months), dysfunctional bleeding (uterine bleeding caused by disorders in the ovary), endometriosis, endometrial cancer, pain in the breast and breast dysplasia.

It is necessary to exclude the presence of a malignant tumor before starting the therapy.

Norethindrone is well absorbed in the gastrointestinal tract after oral administration. The bioavailability is about 50-77% due to the intense primary metabolism in the liver. The maximum concentration of the active substance can be achieved after about 2 h.

Dosage indications for Norlutate

Before using this drug, it is necessary to conduct a thorough general medical and gynecological examination (including breast examination and cytology) and exclude the presence of pregnancy. It is necessary to conduct general examination in the case of long-term use (approximately every 6 months).

Premenstrual syndrome: the initial dose is of 5-10 mg per day (1-2 tablets), starting from the day 16-25.

Dysfunctional uterine bleeding and swelling of the endometrium: take 1-2 tablets per day for 6-12 days. Take the same dose within day 16-25 for the prevention of relapse.

Endometriosis: long-term therapy is recommended (6 months). Take 1 tablet per day within day 5-25 or 1/2 tablets every 2-3 weeks for 4-6 months.

Endometrial cancer: 20-30 mg daily; maintenance dose – 5-10 mg per day.

As contraceptive drug: 1.25-2.5 mg at night, within day 5-21. After that, you should make a 7-day break.

Menopause: take 1 tablet per day (long-term therapy in conjunction with estrogen drugs).

In general, the dose of norethindrone should be individualized depending on the nature of the disease and tolerability of the drug.

If the patient has forgotten to take the tablet, the missed tablet should be taken as soon as possible.

Uterine bleeding during the therapy may be associated with polyps, cancer of the cervix or endometrium, myoma, ectopic pregnancy, thrombocytopenia, thrombasthenia.

Norlutate side effects

Women may experience adverse reactions associated with Norlutate (norethindrone) therapy: breast tenderness, weight gain, genital tract bleeding (in rare cases), digestive disorders, fatigue, skin rash, paresthesia (numbness in limbs). These side effects usually do not occur during repeated cycles of treatment.

Reasons for immediate discontinuation of the drug: migraine headache, unusually severe headache, blurred vision, symptoms of thrombophlebitis or thromboembolic symptoms (e.g., unusual pain in the legs, swelling of the legs, pain associated with breathing and coughing), pain sensation in the chest cavity, immobilization (e.g., after accidents), symptoms of jaundice, hepatitis A, itching of the whole body, sharp increase in blood pressure, pregnancy.

Norlutate contraindications

Norlutate is contraindicated in patients with thromboembolism, thrombophlebitis (inflammation of the walls of veins), cerebrovascular accident, liver disease, abnormal liver function, bleeding from the genital tract of unknown origin, hormone-dependent tumors (including breast cancer). This drug should never be used during pregnancy.

Precautions: bronchial asthma, chronic heart failure, epilepsy, hypertension, migraine, kidney failure, seizures, diabetes, liver disease, hyperlipidemia.

Norlutate interaction

Norlutate should be used with caution simultaneously with hypoglycemic drugs, oral anticoagulants, corticosteroids.

It is not recommended to combine Norlutate with barbiturates, phenytoin, rifampin, cimetidine.

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