Nolvadex (tamoxifen) Coupons, Discounts & Cost
Nolvadex (tamoxifen) is a non-steroidal estrogen antagonist with antitumor activity. One way to save money on the Nolvadex (tamoxifen) retail cost regardless of income and insurance status is to use Nolvadex (tamoxifen) coupons or discount cards from RXCoupons. Use our Nolvadex (tamoxifen) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.
What is Nolvadex (tamoxifen)?
Nolvadex (tamoxifen) is a non-steroidal estrogen antagonist with antitumor activity. It prevents the formation of female sex hormones (estrogens) that stimulate the growth of cancer cells. Thus, tamoxifen slows the progression of cancer.
Nolvadex (tamoxifen) may be administered for the prevention of breast cancer in women who are predisposed to such disease. The drug reduces by almost one third the risk of developing breast cancer.
When should I use Nolvadex (tamoxifen)?
Nolvadex (tamoxifen) is used for:
- estrogen-dependent breast tumors in postmenopausal women;
- breast cancer (including men after castration);
- kidney cancer;
- soft tissue melanoma and sarcoma;
- ovarian cancer;
- prostate cancer (in case of resistance to other drugs);
- endometrial cancer.
When should I NOT use Nolvadex (tamoxifen)?
Nolvadex tablets are contraindicated in the following cases:
- hypersensitivity;
- pregnancy;
- breastfeeding;
- cataracts;
- thrombophlebitis;
- leukopenia, thrombocytopenia.
What should I know about Nolvadex (tamoxifen) side effects?
Nolvadex may cause the following adverse reactions:
- dizziness;
- gastrointestinal disorders and nausea;
- uterine bleeding, endometrial hyperplasia, uterine fibroids, vaginal itching;
- fluid retention;
- hypercalcemia;
- thrombocytopenia, leukopenia;
- alopecia;
- bone pain;
- changes in the retina;
- thromboembolism.
Women: endometrial hyperplasia, vaginal discharge, metrorrhagia, dysmenorrhea, genital itching, amenorrhoea.
Men: reduced potency or libido.
Nolvadex (tamoxifen): instructions for use
Nolvadex dosing regimen should be set individually for each patient, depending on the diagnosis. Nolvadex tablets should be taken without chewing, with a full glass of water. Patients may take the entire dose at once (in the morning) or two doses (in the morning and evening). Patients with breast cancer should use 20-40 mg, patients with endometrial cancer - 30-40 mg. The maximum daily dose is 40 mg. Treatment is often carried out in combination with cytostatic and radiation therapy.
During treatment, patients should monitor leukocytes, blood calcium levels, liver function. Nolvadex is ineffective in the presence of liver metastasis.
What should I know about Nolvadex (tamoxifen) interaction?
Nolvadex (tamoxifen) enhances the effect of anticoagulants. Simultaneous administration of Nolvadex and oral contraceptives containing estrogen may lead to ineffectiveness of both drugs.
Allopurinol enhances the hepatotoxic effects of the drug.
Cytostatic agents significantly increase the risk of blood clots.
Thiazide diuretics increase the risk of hypercalcemia.
What should I know about Nolvadex (tamoxifen) special instructions?
Before starting the therapy, women should undergo a thorough gynecological and physical examination.
Nolvadex causes ovulation and increases the risk of pregnancy. Therefore, women of childbearing age should use safe and effective birth control methods during treatment and within 3 months after treatment.
During Nolvadex therapy, patients should periodically monitor blood coagulation status, liver function, blood pressure. They should consider visiting an ophthalmologist and gynecologist (the drug should be discontinued in case of bloody vaginal discharge or vaginal bleeding).
Patients with bone metastases should periodically monitor the concentration of Ca2 + (the drug should be discontinued in the case of severe hypercalcemia). Nolvadex therapy is ineffective in the treatment of patients with liver metastases.
The drug should be discontinued in case of signs of thrombosis of the lower extremities (leg pain or swelling), thromboembolism, shortness of breath.
Patients with hyperlipidemia need to control cholesterol and triglyceride concentrations in serum.
Patients on Nolvadex therapy should be careful when driving or performing potentially hazardous activities that require high concentration.