FEMARA (letrozole) Coupons, Discounts & Cost

FEMARA (letrozole) Coupons, Discounts & Cost
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Femara (letrozole) Coupons, Discounts & Cost

Femara (letrozole) is a drug belonging to the group of hormonal anticancer agents. One way to save money on the Femara (letrozole) retail cost regardless of income and insurance status is to use Femara coupons or discount cards from RXCoupons. Use our Letrozole coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.

What is Femara (letrozole)?

Femara (letrozole) is a drug belonging to the group of hormonal anticancer agents. It is used for the treatment of malignant breast tumors. Femara has a marked anti-estrogenic activity: it blocks estrogen synthesis both in tumor and in peripheral tissues. The daily intake at therapeutic doses does not affect the synthesis of steroid hormones in the adrenal gland. Therefore, this drug does not require additional therapy with mineralocorticoids and glucocorticoids.

The drug does not cause disorders of the thyroid gland. Moreover, it does not increase the risk of stroke, myocardial infarction, and osteoporosis.

Femara is often used for adjuvant treatment of early-stage breast cancer in postmenopausal females. It significantly reduces the probability for further disease progression and increases the five-year survival for cancer patients with no signs of disease. Femara is also used as first-line therapy in postmenopausal women with hormone-dependent forms of breast cancer.

What should you know about Femara (letrozole) indications?

Femara indications:
– Early-stage breast cancer in postmenopausal women (as adjuvant therapy);
– Early-stage breast cancer in postmenopausal women after standard adjuvant therapy with tamoxifen (as extended adjuvant therapy);
– Treatment of hormone-dependent forms of breast cancer in postmenopausal women (first-line therapy);
– Different types of breast cancer in postmenopausal women (natural or induced menopause), who were previously treated with antiestrogens.

Femara (letrozole) dosage and administration

The drug should be taken at a dose of 2.5 mg (1 tablet) once a day for a very long time. The therapy can last up to five years. If there are signs of progression of the disease, the treatment should be discontinued immediately. Femara tablets can be taken at any time of the day and regardless of the meal.

If you miss a dose, the next one should be taken as soon as possible. Nevertheless, do not exceed the daily dose (to avoid potential systemic effects of the drug).

What should you know about Femara (letrozole) contraindications?

Absolute contraindications: pregnancy and lactation, childhood and adolescence, endocrine disorders. Femara is strictly contraindicated during pregnancy and lactation.

What should you know about Femara (letrozole) side effects?

Femara side effects include:
Digestive tract: dyspepsia, nausea, vomiting, diarrhea or constipation, stomatitis.
Nervous system: dizziness, headache, nervousness, irritability, depression.
Hematopoietic system: leukopenia.
Cardiovascular system: tachycardia, high blood pressure, thrombophlebitis.
Dermatologic reactions: skin rash, itching, sweating, alopecia, angioedema.
Musculoskeletal system: myalgia, arthralgia, osteoporosis.
Other reactions: very often – hot flashes; often – fatigue, asthenia, peripheral edema, weight gain, high cholesterol, anorexia, increased appetite; rarely – weight loss, thirst, hyperthermia (pyrexia), generalized edema.
Femara may cause hot flashes, fatigue, weight gain. The drug should be administered with caution in patients suffering from severe hepatic impairment. Some side effects (dizziness, weakness, etc.) may negatively affect your driving ability.

What should you know about Femara (letrozole) special instructions?

Letrozole pharmacokinetic parameters do not depend on the patient’s age.

Femara should be taken with caution by patients suffering from severe hepatic impairment. In case of accidental overdose, patients should seek medical attention immediately.

Patients with impaired hepatic function may not change the dose of Femara. However, patients should be kept under constant surveillance in case of severe hepatic dysfunction.

The drug should be stored in a dry place inaccessible to children, at temperatures not exceeding 30° C. Femara tablets should not be used after their expiration dates.

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