DAPSONE (diaminodiphenyl sulfone) Coupons, Discounts & Cost

DAPSONE (diaminodiphenyl sulfone) Coupons, Discounts & Cost
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Dapsone (diaminodiphenyl sulfone) Coupons, Discounts & Cost

Dapsone (diaminodiphenyl sulfone) is an antileprosy drug from the sulfone group. One way to save money on the Dapsone (diaminodiphenyl sulfone) retail cost regardless of income and insurance status is to use Dapsone (diaminodiphenyl sulfone) coupons or discount cards from RXCoupons. Use our Dapsone (diaminodiphenyl sulfone) coupons at your online pharmacy and receive up to 75% off the sale price each time you refill your prescription.

What do I need to know about Dapsone (diaminodiphenyl sulfone)?

Dapsone (diaminodiphenyl sulfone) is an antileprosy drug from the sulfone group. It has bacteriostatic, antifungal and antiprotozoal effects.

The drug is active against a broad spectrum of microorganisms, but primarily against Mycobacterium leprae, Pneumocystis carinii. It stops the growth and reproduction of bacteria, but does not cause their death.

Dapsone recommendations for use: Hansen’s disease (leprosy), tuberculosis, dermatitis herpetiformis (Duhring’s disease), Pneumocystis carinii pneumonia (PCP). The drug is also used in mycetoma caused by actinomycetes, rheumatoid arthritis, certain lesions of the skin (systemic lupus erythematosus), granuloma annulare, pyoderma gangrenosum.

Dapsone can be used in combination with corticosteroids in the treatment of dermatomyositis and urticarial vasculitis (when treatment with antihistamines and NSAIDs has no effect). The drug is effective in angioedema and systemic connective tissue diseases.

What should I discuss with my doctor before taking Dapsone (diaminodiphenyl sulfone)?

Do not take Dapsone (diaminodiphenyl sulfone) if you have chronic liver disease, hypersensitivity (including to sulfonamides), severe anemia.

The drug is not recommended in pregnancy and during lactation. The drug should be used only when strictly necessary in the first 4 months of pregnancy and during lactation. Since diaminodiphenyl sulfone is secreted in breast milk, women should stop breastfeeding.

How should I take Dapsone (diaminodiphenyl sulfone)?

The dosage regimen is selected individually. Dapsone can be used in combination therapy at a dose of 50-100 mg per day or 1-2 mg per kg per day. The maximum daily dose is 300 mg.
Leprosy: the average daily dose is 50-100 mg (1-2 tablets) per day.
Dermatitis herpetiformis: treatment should be started with 2 tablets per day (100 mg) for 1 week. Then, the dose can be increased up to 4 tablets (200 mg).
Bullous dermatoses: 50-100 mg 2 times a day (3-5 courses for 5 days with 2-day intervals).
Vasculitis: 50-150 mg per day.

What are the possible side effects for Dapsone (diaminodiphenyl sulfone)?

Digestive system: nausea, vomiting, hepatitis.
Hematopoiesis: hemolytic anemia, agranulocytosis, methemoglobinemia.
Skin disorders: Stevens-Johnson syndrome, toxic epidermal necrolysis, skin rash, exfoliative dermatitis.
Nervous system: headache.
Dapsone may also provoke the following states:
Cardiovascular and hematopoietic system: cardialgia, hemolytic anemia (fever, back pain, loss of appetite, pale skin, unusual weakness), aplastic anemia (including death), agranulocytosis, methemoglobinemia (skin cyanosis, difficulty breathing, etc.), pathological changes in the blood (unusual bleeding, sore throat, fever).
Skin reactions: exfoliative dermatitis (hair loss, skin redness, dryness, itching), erythema nodosum, erythema multiforme, erythema toxicum, toxic epidermal necrolysis.
Nervous system: neurotoxicity (nervousness, insomnia, headaches), mental disorders, including peripheral neuritis (weakness, pain in the legs and arms, numbness), mood changes.
Side effects of allergic nature: Dapsone-induced sulfone syndrome (fever, exfoliative dermatitis, jaundice, lymphadenopathy, anemia).
Gastrointestinal tract: nausea, vomiting, liver damage, jaundice, anorexia (decrease or loss of appetite).

What may happen if I overdose?

Dapsone overdose signs and symptoms: agranulocytosis, leukopenia, infections. Treatment is symptomatic.

How Dapsone (diaminodiphenyl sulfone) interacts with other drugs

Probenecid may decrease the excretion of dapsone and increase its concentration in the blood.

Simultaneous treatment with rifampicin is not recommended.

Dapsone should not be used with barbiturates.

What should I know about Dapsone (diaminodiphenyl sulfone) special instructions?

The drug is mainly used to treat leprosy and dermatitis herpetiformis. It is necessary to monitor indicators of hepatic transaminases, as well as measure reticulocyte and platelet counts during treatment.

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