Casodex (bicalutamide) Coupons, Discounts & Cost
Casodex (bicalutamide) is a non-steroidal anti-androgenic drug used for the treatment of advanced prostate cancer. One way to save money on the Casodex (bicalutamide) retail cost regardless of income and insurance status is to use Casodex (bicalutamide) coupons or discount cards from RXCoupons. Use this Casodex (bicalutamide) coupon at this online pharmacy and receive up to 75% off the sale price.
General information about Casodex (bicalutamide)
Casodex (bicalutamide) is a non-steroidal anti-androgenic drug used for the treatment of advanced prostate cancer. Casodex is prescribed for the treatment of malignant prostate tumors (as monotherapy and in conjunction with surgical methods of therapy: castration, prostatectomy, etc.).
General information about Casodex (bicalutamide) contraindications
Casodex (bicalutamide) should not be used with astemizole, terfenadine, cisapride. It is contraindicated in patients with hypersensitivity to the drug, as well as in women and children.
The drug should be used with caution in patients with impaired liver function, as well as in patients with lactase deficiency, lactose intolerance and glucose-galactose malabsorption.
How to use Casodex (bicalutamide)
The drug is prescribed for men, including elderly patients. The usual dose is 50 mg per day (combined treatment with gonadotropin-releasing hormone analog or surgical castration). Patients with mild hepatic impairment and functional renal impairment should use the same dose as other patients.
General information about Casodex (bicalutamide) side effects
Patients taking Casodex (bicalutamide) may experience unwanted side effects: skin rash, gynecomastia (especially in case of chronic administration of the drug), asthenia, breast pain, chest pain, drowsiness, dizziness, depression, anorexia, hot flushes, abdominal pain, itching, constipation, nausea, indigestion, weight gain, loss of appetite, dry skin, flatulence, alopecia, hirsutism, hematuria, erectile dysfunction, edema, anemia, jaundice, hepatotoxicity, angioedema, urticaria, hypersensitivity reactions, interstitial lung disease, hepatic failure, cholestasis. These abnormalities are usually mild and transient.
Common side effects: Reproductive system and breast: breast pain; Gastrointestinal disorders: diarrhea, nausea, vomiting; Hepatobiliary system: jaundice; Immune system: hypersensitivity reactions, including urticaria and angioedema; Respiratory disorders: interstitial lung disease. Possible side effects: Circulatory system: heart failure; Gastrointestinal system: anorexia, dry mouth, dyspepsia, constipation, flatulence; Central nervous system: dizziness, insomnia, somnolence, decreased libido; Respiratory system: shortness of breath; Genitourinary system: impotence, nocturia; Metabolic disorders: diabetes mellitus, hyperglycemia, edema, weight gain, weight loss; General disorders: pain in the abdomen, headache, fever; Other reactions: anemia, alopecia, rash, sweating, hirsutism. Some of these effects are more likely to develop in elderly patients.
Casodex is well tolerated by most patients. Only in rare cases severe adverse reactions may require termination of Casodex therapy.
Casodex (bicalutamide) specific indications
Patients with impaired liver function should periodically monitor liver function during treatment. In most cases, liver function changes have been observed within the first 6 months of therapy. If severe disorders occur, treatment interruption is recommended.
Caution should be exercised when you use Casodex with CYP3A4-metabolized drugs.
Patients with lactose intolerance should keep in mind that Casodex tablets include lactose monohydrate.
Casodex may cause dizziness and drowsiness. Therefore, patients need to be careful when driving.
Casodex (bicalutamide) interactions
Casodex (bicalutamide) may cause undesirable effects when combined with some medicines. Patients taking Casodex should reduce the dose of calcium channel blockers and cyclosporine (it is recommended to carefully monitor the concentration of cyclosporine in the blood).
Drugs that are potent inhibitors of hepatic microsomal enzymes (ketoconazole, cimetidine) may increase the concentrations of bicalutamide, and possibly increase the risk of side effects.
Casodex enhances the pharmacological effect of anticoagulant drugs derived from coumarin.
Concomitant use of Casodex with terfenadine, astemizole, and cisapride is contraindicated.
Casodex (bicalutamide) conditions of storage
Store in a place inaccessible to children, at temperature up to 30° C.