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What is Benicar (olmesartan medoxomil)?
Benicar (olmesartan medoxomil) is a popular drug for reducing blood pressure. It is widely used for the treatment of essential hypertension.
Benicar (olmesartan medoxomil) contraindications
Benicar (olmesartan) is contraindicated in the following conditions: obstruction of the bile ducts, renal insufficiency, pregnancy, lactation, hypersensitivity to olmesartan.
The drug should be used with caution under the following conditions or diseases: aortic or mitral stenosis, hypertrophic obstructive cardiomyopathy, primary aldosteronism, hyperkalemia, hyponatremia (risk of dehydration, hypotension, renal failure), chronic heart failure, bilateral renal artery stenosis, coronary artery disease, cerebrovascular disease, abnormal liver function.
Benicar should not be used together with diuretics. It is also not recommended for children (up to 18 years of age) and elderly patients.
Benicar (olmesartan medoxomil) dosage information
Take the drug every day at the same time (1 time per day), regardless of the meal.
The recommended starting dose for adults is 10 mg (1 tablet) 1 time per day. The dose may be increased to 20 mg per day. If necessary, the dose can be increased to the maximum level - 40 mg per day (a diuretic may be added). The maximum daily dose is 40 mg.
Benicar (olmesartan medoxomil) overdose
Symptoms: reduction of blood pressure. Treatment: try gastric lavage and activated charcoal.
Benicar (olmesartan medoxomil) side effects
Possible Benicar side effects are listed below: Cardiovascular system: angina pectoris, tachycardia, reduction of blood pressure. Metabolism: hypertriglyceridemia, hyperuricemia, hyperkalemia. Hematopoietic system: thrombocytopenia. Central nervous system: dizziness, headache. Respiratory system: pharyngitis, rhinitis, cough, bronchitis. Digestive system: diarrhea, dyspepsia, gastroenteritis, abdominal pain, nausea, vomiting (very rarely). Musculoskeletal system: back pain, bone pain, arthralgia, arthritis, muscle cramps, myalgia. Urinary system: hematuria, urinary tract infections, acute renal failure (very rarely). Skin disorders: itching, rash, angioedema, allergic dermatitis, urticaria (very rarely). Other reactions: chest pain, flu-like symptoms, peripheral edema, asthenia, fatigue, malaise, drowsiness.
Benicar (olmesartan medoxomil) interactions
It is not recommended to use Benicar with potassium-sparing diuretics, salt substitutes containing potassium, or other agents that may increase the level of potassium in your blood (e.g., heparin).
The antihypertensive effect of Benicar therapy can be enhanced if you use other antihypertensive agents.
Antacids (magnesium and aluminum hydroxide) may moderately decrease the bioavailability of olmesartan.
Olmesartan should not be used in combination with drugs containing lithium.
Benicar (olmesartan medoxomil) special instructions
Symptomatic hypotension (especially after the first dose) may occur in patients with reduced levels of sodium due to therapy with diuretics, as well as due to diarrhea or vomiting.
As with any antihypertensive drug, excessive reduction of blood pressure in patients with ischemic heart disease or cerebrovascular insufficiency may lead to myocardial infarction or stroke.
There is an increased risk of severe hypotension and renal insufficiency in patients with bilateral renal artery stenosis who are on Benicar therapy.
Benicar therapy may cause hyperkalemia if the patient suffers from renal impairment or chronic heart failure. Such patients should regularly monitor the level of potassium in the blood.
Caution should be exercised when driving and performing potentially hazardous activities that require high concentration and psychomotor speed reactions (Benicar may cause dizziness and weakness).
Benicar (olmesartan medoxomil) conditions of storage
The drug should be stored out of reach of children, at a temperature not higher than 30° C. Do not use this drug after the expiration date.